Detailed Notes on megatomi.com
Detailed Notes on megatomi.com
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Our new Clear+ tissue clearing strategy is the only approach that delipidates samples without having improve in morphology and with minimum impact on structural integrity.
Megatome is a vibrating microtome intended to portion a broad array of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With superior blade vibrating frequency and minimized blade deflection, Megatome permits significant-throughput tissue sectioning with uniform area profile, along with minimum tissue injury and information decline.
Antibodies may perhaps take weeks to diffuse by way of just a few millimeters of tissue, by using a steep labeling gradient from surface area to core.
Megatome is made for accuracy: the blade vibrates at a greater frequency and larger amplitude variety than other microtomes, and includes a distinctive deflection Manage system.
SE works by using a rotational electrical discipline to disperse extremely electromobile molecules (like antibodies or surfactant micelles) throughout a porous sample without harming electrically billed constructions within the tissue. This enables two-four day clearing of intact organs,
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Megatome can be a novel microtome that allows for top-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with small tissue harm and knowledge decline.
eFLASH is really a immediate tissue labeling strategy that permits for uniform full-organ staining in 20 rounds of labeling.
The SmartSPIM mild sheet microscope presents unparalleled resolution and acquisition pace all over intact tissue volumes, although its modular structure lets you upgrade and personalize individual parts.
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